Bindley Bioscience Center

Role(s)	• Located in Discovery Park at Purdue University, the Bindley Bioscience Center provides an integrated platform of infrastructure, advanced instrumentation, disciplinary expertise, data analysis, consulting, and training to advance life sciences research • Bindley provides a unique infrastructure to support interdisciplinary research. Laboratory space and high-end scientific equipment is shared and available to support diverse projects. • Bindley core facilities offer scientific expertise and access to high -end instrumentation to the research community. The expert staff can collaborate on projects, as well as offer research consultation and technical support
Mission	The vision of the Bindley Bioscience Center is to integrate interdisciplinary life sciences research with engineering to create unique opportunities to solve global challenges in the life sciences.
History	2005 - Created as a Center in Purdue's Discovery Park with funding from William E. Bindley 2010 - Received NIH Construction grant to build an addition dedicated to cancer research 2014 - Multidisciplinary Cancer Research Facility opens as a part of Bindley
Org	• Staff of 13 research scientists • Two Research Faculty • Two operations and administrative staff • One IT specialist Leadership: • Ramaswamy Subramanian: Bindley Director (subram68@purdue.edu) • Natasha Nikolaidis: Associate Director of Operations (nnikolai@purdue.edu) • Bruce Cooper: Associate Scientific Director (brcooper@purdue.edu)
Board	N/A
Finance	• Annual support from Purdue Office of Research • Support from Purdue Center for Cancer Research, Center for Plant Biology, and various departments • Seven core facilities generating recharge income • Sponsored program funding from a variety of sources including NIH, NSF, DOD, and USDA
Data Source	Various research projects
Data Access	Data are generated in the core facilities via individual faculty projects, and owned by the researchers. Samples, products derived from samples, data obtained from the analysis of samples, and data and analyses obtained from a facility user are considered confidential, and are not to be shared, published, reanalyzed, reprocessed, or in any other way shared or used for additional analyses without the facility user's express written permission.
Tech Capabilities	• Global and targeted metabolomics, proteomics, and lipidomics • Protein and small molecule identification, and quantitation • Analysis of post-translationally modified proteins, peptides, and protein complexes • Cell cycle analysis, immunophenotyping, antibody binding evaluation • Drug response and apoptosis assays • First in animal PK/PD studies, ADME, and bioavailability studies • Implantable device testing • Live animal imaging -fluorescent, bioluminescent, C, or nuclear • Live cell and deep tissue imaging • High resolution imaging for multiple sample types and preparations • High throughput and next generation genomic sequencing • CRISPR vector construction and edited cell lines • Statistical and bioinformatic collaboration, data analysis support
Projects	Bindley focuses on the following key research areas: • Cancer Research • Infectious Diseases • Instrument technology development • Basic Biomedical Science • Translational Research
Future Focus	Opportunities to launch scientific discoveries toward commercialization, supporting promising academic discoveries still in the laboratory, as well as fragile early-stage companies so that these entities can more rapidly and effectively obtain their proof-of-concept data or build their prototype to attract external funding and move to the next stage.
Talent Development	Bindley employs both graduate and undergraduate students in the core research facilities.
Data Sharing Agreements	Data sharing agreements are negotiated between individual researchers
Programs/ Publications	Newsletters: https://www.purdue.edu/research/life-sciences/news/newsletter-archive.php